+91 80 6596 3132
sales@anodynetherapy.co.in






Overview

Clinical Studies

The Anodyne® Therapy System was the first infrared light therapy product cleared by the United States FDA in 1994, and it remains one of the few evidence based infrared light therapy modalities on the market today.

Many manufacturers reference clinical data completed using other light therapy products – and have little to no proprietary clinical data on their specific devices.

There are 14 published peer reviewed studies demonstrating the exceptional outcomes with Anodyne® Therapy Systems.

Throughout these studies, the term MIRE™ is also referenced. This term represents the wordsMonochromatic Infrared Energy and is a trademark of Anodyne® Therapy technology specifically.

These clinical studies have been published in such journals as Diabetes Care, Practical Pain Management, Age and Ageing and Endocrine Practice.

To request copies of these clinical studies, please click here to contact us.


If you can answer YES to any of the images above you are likely anexcellent candidate for treatment with either Professional or Consumer Anodyne® Therapy Systems.

 Clinics using Anodyne therapy have seen complelling results for a variety of conditions ranging from:
- Diabetic peripheral neuropathy (loss of sensation or feeling)
- Slow healing wounds
- Diabetic ulcers
- Sprains
- Arthritis
- Stress Fractures
- Bursitis
- Edema
- Tendonitis
- Carpal tunnel syndrome
- Temporal Mandibular Joint disorders ("TMJ")

Method of Action

The mechanism of action underlying pain relief associated with Anodyne Therapy / MIRE may be due, in part, to a combination of topical heat and anincreased local release of nitric oxide that has been reported using this wavelength (890nm) of near infrared light energy. The source of released nitric oxide may be endothelial cells or red blood cells, or both.

Nitric oxide has been studied for many years; however, interest has peaked in the last 10-15 years as a result of the discovery of the role of nitric oxide as a signaling mechanism in the human body. The researchers of this discovery were awarded the Nobel Prize in Physiology in 1998.

Clinical Research has linked nitric oxide with:

method-of-action

Increases in local circulation – vasodilation
Reduction of pain
Reduction in inflammation
Angiogenesis
Collagen synthesis

Light mediated vasodilation was first described by R. F. Furchgott, in his nitric oxide research that led to his receipt of a Nobel Prize in 1998. Later studies conducted by other researchers confirm and extend Furchgott’s early work and demonstrate the ability of infrared light or photo energy to influence thelocalized production or release of NO and stimulate vasodilation through NO’s effect on cGMP.

Wavelength

Over the years, some wavelengths of infrared light have been proven to be more effective than other wavelengths in terms of increasing circulation. The wavelength of 890 nm that is used with Anodyne Therapy Infrared Products has been validated through our published clinical data, and also throughindependent testing.

The video below is that of a human hand with an Anodyne Infrared Therapy Pad placed on the palmar aspect. You can see the light passing through the cracks of the fingers, as well as through the skin. However, you can see that the blood vessels are very dark, which means that

BACKGROUND

Anodyne therapy is a type of light therapy that is used to help relieve the symptoms of pain, stiffness, muscle spasms, and circulation irregularities. This form of treatment is usually given in addition to physical therapy. It works by relieving pain and/or increasing circulation in the area where the patient is experiencing pain. Anodyne therapy is marketed and sold by Spectropad Systems, which manufactures the device that administers the therapy. The scientific term for Anodyne therapy is monochromatic infrared photo energy (MIRE). MIRE is the type of energy that is used in this form of therapy.

Light therapy, also known as phototherapy, is the use of a specialized machine to emit only a specific wavelength of the light spectrum via lasers, LEDs, fluorescent lamps, dichroic lamps, or very bright, full-spectrum light, for a prescribed amount of time. Each wavelength in the light spectrum is said to possess specific qualities. Generally, the affected body part is exposed in light therapy. Advocates claim that each wavelength may coincide with beneficial symptom relief of a particular medical condition. Light therapy machines are able to offer more of a particularly useful wavelength than would be available by exposure to direct sunlight.

According to the American Physical Therapy Association, the goal of physical therapy or physiotherapy is to improve mobility, restore function, reduce pain, and prevent further injury by using a variety of methods, including exercises, stretches, traction, electrical stimulation, and massage. Physical therapy (PT) is commonly used for musculoskeletal injuries, joint pain or disorders, low back pain, cerebral palsy, and rehabilitation after injury or surgery, including heart surgery or mastectomy. Various types of physical therapy address specific problems. Musculoskeletal physical therapy uses massage and joint movement to increase strength, motor control, and flexibility. Cardiopulmonary physical therapy treats lung and heart conditions, such as cerebral palsy, asthma, and post-heart attack rehabilitation, by clearing the lungs of mucus, ventilating the lungs to ease breathing, or exercising to increase a patient’s ability to move. Neurological physical therapy works to restore balance, coordination, and motor function through repeated exercises for patients with spinal injury, Parkinson’s disease, Alzheimer’s disease, and other brain and nerve disorders. Integumentary physical therapy uses wound cleaning, scar prevention, and scar reduction to help patients with wounds, burns, and other skin-related problems.

Anodyne therapy comes from the word anodyne, meaning a medical treatment that soothes or relieves pain. Anodyne therapy was first used in 1994. All forms of Anodyne therapy use infrared light. Pads that emit the light are applied to the surface of the skin. At times, Anodyne therapy will resolve symptoms in one or only a few sessions. For other individuals, however, ongoing Anodyne therapy may be necessary to experience relief from symptoms. Anodyne therapy may help a patient cope with the symptoms of their medical condition because the pain relief and increased circulation provided by the near infrared light may aid in improving a patient’s balance, range of motion, endurance, strength, and flexibility.

Eleven clinical trials have been conducted to evaluate the efficacy of Anodyne therapy for several different medical conditions. Though the results of these studies appear promising, larger studies need to be conducted before a firm conclusion can be drawn.

As a relatively inexpensive treatment, Anodyne therapy is gaining popularity in the United States. Some health insurances reimburse patients for near MIRE. Anodyne therapy is now being investigated for a number of uses, including diabetic neuropathy (deterioration of the spinal cord and its nerves due to diabetes).

SYNONYMS

Cardiopulmonary physical therapy, infrared light, integumentary physical therapy, light therapy, MIRE, monochromatic infrared photo energy, musculoskeletal physical therapy, neurological physical therapy, occupational therapy, phototherapy, physical therapy, PT.

Anodyne therapy for neuropathy

For hundreds of years, diabetics and people with poor circulation have had to deal with neuropathy.Neuropathy is caused by damage to your nerves which results in a loss of sensation, weakness and twitching, amongst other symptoms. Solving neuropathy is easy in theory, but not so easy in execution. Many diabetic sand other neuropathy sufferers have tried for years to find a cure to this dreaded disorder. One of the most promising developments in recent years has been found in anodyne therapy for neuropathy.

Anodyne therapy for neuropathy is a therapy for neuropathy that is centered on the use of an infrared light. During anodyne therapy for neuropathy, an infrared light that is embedded into a cloth or plastic sleeve is placed on the spot where a patient has experienced damage to his or her nerve endings or is experiencing pain, twitching or other symptoms of neuropathy. The light turns on and is said to go deep inside the tissues with the damaged nerves. This journey into the tissue is said to dilate the blood vessels within and improve blood flow and circulation through the tissue. With the resurgence of blood comes the feeling back into the area along with the decrease of twitching, pain and all the other symptoms of neuropathy.

How does anodyne therapy for neuropathy work?

Anodyne therapy for neuropathy is said to work by stimulating your cells to create and release nitric oxide. Nitric oxide is an extremely important messenger within your body. It floats around sending messages from cell to cell about blood flow the key to the problems behind neuropathy. When nitric oxide does its work, your muscles soften and relax and your blood vessels widen which increases your blood flow and corrects your circulation.

Does anodyne therapy for neuropathy work?

So far, clinical trials for anodyne therapy for neuropathy have shown positive results and it is currently an approved treatment for neuropathy in over 3,000 doctor’s offices. One of the major medical groups to embrace anodyne therapy for neuropathy is podiatrists. Podiatrists deal with many neuropathy patients since the feet are a prime candidate for reduced blood flow and compromised circulation in diabetics and non diabetics alike. Diabetes care magazine has also sang the praises of anodyne therapy for neuropathy stating that it demonstrates, “strong benefits” to diabetics fighting neuropathy. It has also been approved by the United States’ Food and Drug Administration for treatment of neuropathy.

How long as anodyne therapy for neuropathy been in use?

Anodyne therapy for neuropathy was first brought onto the medical scene in 1994 so there has been plenty of time to explore both the efficacy of treatment and potential side effects.

How is anodyne therapy for neuropathy administered?

The treatment schedule will vary depending on the location of your neuropathy and its intensity. For the sake of clinical trials, treatment took place over a two week time period and involves a total of six treatments each lasting thirty minutes. It is possible your anodyne therapy for neuropathy treatment schedule will be similar to that of the clinical trials.

Is anodyne therapy for neuropathy safe?

Having been approved by the Food and Drug Administration, it certainly seems to be a safe treatment for diabetic and non-diabetic neuropathy. In addition, it is safe for use over pacemakers, implants and all parts of the body. This certainly infers safety as does the 15 year history of the treatment. Talk to your primary care physician today to find out if anodyne therapy for neuropathy might be the right treatment for your painful and troubling neuropathy.

Did You Know?

Anodyne Therapy is cleared by FDA for temporarily increasing circulation and reducing pain, stiffness and muscle spasm. Therefore, any condition that would benefit from these indications may benefit from the effects of this infrared therapy device.
Some patients feel pain relief in the first treatment, while others need 10 or more treatments to feel improvement. Generally speaking, if patients have not felt some improvement within 20 treatments, infrared therapy may not be effective for their conditions.

Anodyne Infrared Light Therapy

What is Anodyne?

Anodyne is a treatment that uses light energy, which dramatically increases circulation in the area to which it is applied. Light-emitting diodes are fitted into flexible pads that can be applied directly to the skin on any affected part of the body. The light energy helps increase blood flow by delivering healing cells and nutrients to the injured site.

How does Anodyne therapy work?

Anodyne therapy consists of 10 to 20 sessions lasting 45 minutes each. During this time, energy is penetrating your tissues increasing circulation up to 400 percent. It is this increase in circulation that results in relief of pain and rapid wound healing.

Nitric Oxide is the key

Light energy helps your body release a gas called Nitric Oxide from your own red blood cells. Three scientists received the Nobel Prize in Physiology of Medicine in 1998 for their discoveries surrounding Nitric Oxide and its effect on the cardiovascular system (Furchgott, Ignarro, and Murad). This powerful molecule plays a critical role in the health of your arteries; Anodyne increases its production resulting in pain relief and improved circulation. To learn more about Nitric Oxide and the 1998 Nobel Prize go tohttp://nobelprize.org/.

Anodyne for Diabetic Peripheral Neuropathy

Are you experiencing loss of sensation, loss of balance, chronic pain, or loss of feeling in your extremities?
Before experiencing wounds or diabetic ulcers, patients affected by diabetic peripheral neuropathy suffer from loss of sensation, loss of balance, chronic pain, or loss of feeling in their extremities. This is of particular concern for health care providers because patients cannot identify (or sometimes feel) the source of the problem; therefore, often recognize the symptoms when they have progressed and circulation is severely compromised. Wounds or diabetic ulcers left untreated can lead to amputations. Once serious complications manifest, an approach to treatment may involve the surgical placement of stents and the use of prescription drugs.

Anodyne offers a new alternative. It is a therapy that can be used to intervene at the early stages of disease in order to prevent the more serious complications. Depending on the severity of the disease Anodyne may or may not be used in conjunction with prescription drugs. For those needing prescription drugs in conjunction with Anodyne for their neuropathy treatment, at EMMC the long-term goal is to reduce their list of medications and to place them on alternative natural options. To learn more about our recommended natural options, read our L-Arginine and Vitamin D sections.

Anodyne for Chronic Pain & Poor circulation

If you suffer from any condition distinguished by pain and inflammation or a condition characterized by poor circulation, anodyne provides a painless, non - invasive treatment option for you.
Anodyne is often associated with the treatment of diabetic complications such as neuropathy, but its benefits extend far beyond. Our clinic sees compelling results for a variety of other conditions ranging from:

Arthritis
Bursitis
Edema
Tendonitis
Carpal tunnel syndrome
Sprains
Diabetic peripheral neuropathy (loss of sensation or feeling)
Temporal Mandibular Joint Disorders (“TMJ”)
Slow healing wounds
Diabetic ulcers
Stress Fractures

Anodyne Therapy System Tips

The Anodyne Therapy System is a procedure that claims to treat chronic poor circulation, muscle pain and stiffness, diabetic neuropathy and arthritis. The treatment involves using low-level light therapy to relieve these symptoms. If you are considering Anodyne therapy there are some things you should know.

Therapy

Anodyne claims that its light therapy improves circulation and relieves painful symptoms by stimulating the release of nitric oxide in the bloodstream. The light penetrates 3 to 5 cm deep into body tissue, reacting with hemoglobin and freeing nitric oxide. Nitric oxide causes dilation of nearby blood vessels and increases circulation, potentially bringing pain relief to affected areas.


Access

When seeking Anodyne therapy, make sure you find a certified clinician with labeled Anodyne equipment. Anodyne therapy can be administered at a hospital or outpatient clinic. Also, many home-care services offer this therapy for patients who cannot leave their homes.


Frequency

Anodyne therapy can be expensive and is not always covered by insurance, so don’t receive more sessions than you need. Begin with only a few treatments per week, increasing the regimen if pain persists. The average patient receives light therapy three times per week for four weeks. Each session lasts approximately 30 minutes. For severe symptoms, Anodyne therapy is performed up to three times daily.


Precautions

Anodyne therapy should not be used near cancerous growths or a pregnant woman’s abdomen. Also, complications can arise if the light therapy is combined with heating or cooling agents, such as Bengay.

Effectiveness

Several studies have cast doubt on the effectiveness and legitimacy of Anodyne infrared treatment. While a few experiments have shown minor positive results of this therapy, more substantial and credible evidence is necessary to prove the effectiveness of this treatment. Most objective researchers have concluded that   infrared therapy has no significant effect on muscle pain, stiffness, diabetic neuropathy and arthritis. However, this therapy is safe; if you have the money and time, test out Anodyne therapy to see if it works for you.


How to Use Anodyne

The Anodyne infrared therapy system uses pads that emit infrared light, which penetrates the skin and increases circulation in the blood vessels. According to its manufacturer, the increased circulation relieves pain and stiffness. Manufactured in Tampa, Florida, the medical devices help patients in clinical settings and at home. Health care professionals, such as therapists, nurses, podiatrists and chiropractors, use these devices to provide an alternative to drugs. Two types of Anodyne devices are available for home use: Freedom 300 for the feet and legs, and Consumer Model 120 for any part of the body.
Difficulty: Easy

Instructions

Connect the electric plug that comes with your Anodyne home device to a power socket.
2. Place the therapy pad against the area to be treated. If you are using your leg into the calf therapy pad and place your foot on the foot therapy pad.
3. Pull the strap to get a snug fit and hold the device in place using the Velcro.
4. Turn on the switch of the device and wait for the green light to come on. Let the Anodyne device provide treatment for 40 minutes

Increases in Circulation

research_blood_vessels

Circulation increases were measured by a Moor Scanning Laser Doppler after a 20 - 30 minute Anodyne Therapy treatment.

Brighter areas in the images below indicate increased circulation.

Before Treatment
After Treatment
Heel
Up to 3200% increase
Lower Back
Up to 1300% increase
Elbow
Up to 1300% increase
Knee
Up to 2000% increase

baseline

Baseline
400% Increase
MIRE
40% Increase
MIRE Placebo (Warmth)
Foot on left treated with Anodyne (MIRE) showed a 400% increase in circulation while foot on right treated with a placebo heat treatment showed only a 40% increase in circulation.

Duration of Circulation Increase vs. Heating Pad

Pre Scan
Delayed Post Scan
Pre Scan Anodyne
4 hours after >> Anodyne® Therapy
Post Scan Anodyne
FLUX: 124
FLUX: 328
164% increase
Pre Scan
Delayed Post Scan
Pre Scan Heat
2 hours after >> Heating Pad
Post Scan Heat
FLUX: 158
FLUX: 87 
45% decrease



Indications and Safety


Indications

Anodyne Therapy Professional Systems are cleared by the FDA for temporarily increasing circulation andreducing pain, stiffness and muscle spasm.

Any condition, whether acute or chronic, that would benefit from these indications may benefit from the effects of this infrared therapy device.

Clinical applications include treatment of: acute pain/ injuries, muscle spasm, stiffness and pain and or poor circulation caused by chemotherapy, diabetes, vascular diseases, etc.

Safety

Anodyne® Therapy may be used over or near
Anodyne® Therapy may NOT be used over or near
    Any part of the body – including the spine
    Metal implants, plates, pins and screws
    Pacemakers
    Defibrillators
    Active cancerous tumors
    The womb during pregnancy
    Topical heating or cooling agents, or their residuals
    Pain patches, or their residuals

Indications and Safety

    Anodyne Therapy Professional Systems are cleared by the FDA for temporarily increasing circulation andreducing pain, stiffness and muscle spasm.

    Any condition, whether acute or chronic, that would benefit from these indications may benefit from the effects of this infrared therapy device.

    Clinical applications include treatment of: acute pain/ injuries, muscle spasm, stiffness and pain and or poor circulation caused by chemotherapy, diabetes, vascular diseases, etc.

    Safety

    Anodyne Therapy may be used over or near
    Anodyne Therapy may NOT be used over or near
      Any part of the body - including the spine
      Metal implants, plates, pins and screws
      Pacemakers
      Defibrillators
      Active cancerous tumors
      The womb during pregnancy
      Topical heating or cooling agents, or their residuals
      Pain patches, or their residuals

Treatment Protocol


The treatment protocols below are abbreviated – full treatment. 
Instructions are provided in our Product Manual and Online Training Programs.

Condition Tx Time Tx Frequency Number of Tx Pads
Chronic Foot/Leg Pain
Due to diabetes, chemotherapy,
poor circulation etc
30-35 min
3 x per week - lifetime
home maintenance necessary
4 per limb
Back Pain
20-30 min
2 - 3 x per week until condition resolves
As needed (4+)
Neck Pain
20-30 min
2 - 3 x per week until condition resolves
As needed (2+)
Hand/Wrist Pain
20-30 min
2 - 3 x per week until condition resolves
As needed (2+)
Plantar Foot Pain
20 -30 min
2 - 3 x per week until condition resolves
2 per affected foot

Pad Placement

    Upper Body Pad Placement
Neck and Upper Back
Shoulder
Face or Jaw
safe_usage_neck_upper_back
safe_usage_shoulder
safe_usage_face_jaw
Wrist
Elbow
 
safe_usage_wrist
safe_usage_elbow1
 
Lower Body Pad Placement
Lower Back
Foot & Leg
Knee
safe_usage_lower_back
safe_usage_foot_leg
safe_usage_knee
Heel
Ankle
Pads may be attached to cover larger treatment areas
safe_usage_heel
safe_usage_ankle
safe_usage_pads

Benefits and Duration

    How soon will patients feel better and how long will their relief last?

- Some patients feel pain relief in the first treatment, while others need 6 or more treatments to feel improvement.

- Generally speaking, if patients have not felt some improvement within 12 treatments, infrared therapy may not be effective for their condition

- Anodyne Infrared Therapy relieves pain temporarily. Pain and poor circulation caused by chronic conditions will require lifetime use of a consumer system for long-term symptomatic relief.

Study Summaries

Throughout these studies, the term MIRE is also referenced. This term represents the words Monochromatic Infrared Energy and is a trademark of Anodyne Therapy technology specifically.

Pain Study #1
Journal:
Diabetes Care, Volume 27(1), January 2004
Study Site(s):
Joslin Center for Diabetes at Morton Plant Hospital
Number of Subjects:
27 (All Diabetic)
Study Design:
Prospective, Randomized, Double Blind, Placebo Controlled
Protocol Used:
All subjects in the study had chronic pain in the lower extremities. Subjects initially received treatment with active therapy pads on one limb and sham pads on the other limb 3 times per week for 40 minutes each vist for 2 weeks (6 treatments). This was followed by six active treatments of the same duration administered to both limbs duing the following 2 weeks.
Pain Endpoint:
Numeric Visual Analog Scale from 0 - 10 (10 being the worst pain)
Results :
Group VAS Baseline After 6 MIRE Treatments After12 MIRE
Treatments
P Value
1 (N=18) 4.2 + 2.3 3.2 + 1.9 2.3 + 1.7 <0.0001
2* (N=9) 4.2 + 3.9 2.6 + 2.3 2.0 + 2.3 NS
* Patients more impaired
Conclusion:
The results of the study demonstrate that treatments with near-infrared photo energy, MIRE delivered in the manner specified in the study protocol resulted in a significant reduction in lower extremity pain.


Pain Study #2
Journal:

Diabetes and Its Complications, Volume 20(2),2006

Study Site(s):
Multiple Site
Number of Subjects:
2239 (1395 Diabetic; 844 Non-Diabetic)
Study Design:
Multiple Site Retrospective Chart Review based on Prospective, Repeated Measures Analysis
Protocol Used:
All subjects in the study had chronic pain in the lower extermities. The average treatment protocol was 3 x per week for 30-45 minutes for 5 weeks and included physical therapy interventions such as therapeutic exercise, neuromuscular re-education and/or gait training.
Pain Endpoint:
Numeric Visual Analog scale from 0 - 10 (10 being the worst pain)
Results :

Patients Reporting Significant Pain Pre and Post Treatment

Pre Post # Improved % Improved
1563 33 1530 98%

Changes in Pain on 11 point VAS (0-10; 10 being the worst pain)

Pre Post # Points Improved P-Value % Improved
7.2 ± 2.2 2.4 ±2.1 4.8 ± 2.4 <0.0001 67%
Conclusion:
MIRE™ treatments are associated with a reduction in pain, even in patients with lower extremity pain levels between 8-10 on a 0-10 point scale. 


Pain Study #3
Journal:

Physical and Occupational Therapy in Geriatrics, Volume 24(2), 2006

Study Site(s):
Genesis Medical Center (Davenport, IA), Premier PT (Evergreen Park, IL, Orland Park, IL and Hinsdale, IL), Westside Retirement Village (Indianapolis, IN), Sonoma Valley Hospital (Sonoma, CA), Helmwood Healthcare (Elizabethtown, KY)
Number of Subjects:
272 (128 Diabetic, 144 Non-Diabetic)
Study Design:
This was a retrospective Chart Review in seven facilities and was based on Prospective, Repeated Measures Analysis.
Protocol Used:
All subjects in the study had chronic pain in the extremities. The therapy intervention included Anodyne® Therapy for pain and circulation and physical therapy interventions such as therapeutic exercise, neuromuscular re-education and/or gait training 3 x per week for an average of 6 weeks.
Pain Endpoint:
Numeric Visual Analog scale from 0 – 10 (10 being the worst pain)
Results :

Patient Demographics (Pre-Treatment)

Total
Patients
272
Male
135
Female
137
Agea
69 ± 12.3
Mean Number of Treatments
18 ± 10.2
Treatment Time (in minutes)
34.2 ± 9.4

Pain Pre and Post Treatment Results

All Patients (Pain > 4) (n = 257)
VAS Pre-Treatment 7.7 ± 1.2
VAS Post-Treatment 4.8a ± 2.2
VAS Decreases 2.9 ± 2.2
% Pain Reduction 38%
Horrible to Excruciating Pain (VAS 8.5-10) (n = 37)
VAS Pre-Treatment 9.4 ± 0.5
VAS Post-Treatment 4.8a ± 2.7
VAS Decreases 4.6 ± 2.9
% Pain Reduction 49%
Distressing Pain (VAS 6.5-8) (n = 189)
VAS Pre-Treatment 7.8 ± 0.4
VAS Post-Treatment 5.0a ± 1.9
VAS Decreases 2.8 ± 1.9
% Pain Reduction 36%
Discomforting Pain (VAS 4-6) (n = 31)
VAS Pre-Treatment 5.3 ± 0.9
VAS Post-Treatment 3.5a ± 2.5
VAS Decreases 1.8 ± 2.4
% Pain Reduction 34%
a = Values expressed as mean ± SD; All post treatment measures are P<0.0001 vs. Pretreatment
Conclusion:
Use of MIRE™ in combination with other physical therapy interventions is associated with reduced lower extremity pain.

Pain Study #4
Journal:

Age and Ageing, Volume 35(1), 2006

Study Site(s):
Multiple Sites
Number of Subjects:
252 (All Diabetic)
Study Design:
Retrospective Chart Review and Patient Questionnaire
Protocol Used:
All subjects in the study had chronic pain in the lower extremities. The initial therapy intervention included Anodyne® Therapy/MIRE™ for pain and circulation and physical therapy interventions such as therapeutic exercise, neuromuscular re-education and/or gait training. Patients then used an Anodyne Therapy System at home for an average of 8 months after the initial treatment in a clinical setting.
Pain Endpoint:
Numeric Visual Analog scale from 0 – 10 (10 being the worst pain)
Results :

Pain Reduction Based on Average Number of Months Using MIRE™

1-3 3-6 6-9 9-12 12+
# of Patients
36 33 22 94 67
Ave. Months after MIRE Clinical Treatment
1.2 4.0 6.7 10.1 13.3
Mean Age
75 74 76 76 76
Male/Female
23/14 20/13 9/13 44/50 40/27
% of Patients Reporting Reduction in Pain
94% 80% 91% 85% 91%
Conclusion:
The medical records indicated that 220 out of 252 patients (87%, p< 0.0001) obtained substantial reduction in lower extremity pain. When patients have continuing access to MIRE™ in their homes following clinical treatment, there is a significant reduction in pain. 

Pain Study #5
Journal):

Practical Pain Management, Volume 7(6), 2007

Study Site(s):
Multiple Sites
Number of Subjects:
493 (248 Diabetic; 245 Non-Diabetic)
Study Design:
Multiple Site Retrospective Chart Review based on Prospective, Repeated Measures Analysis in combination with patient phone survey on prescription pain medication use.
Protocol Used:
All subjects in the study had chronic pain in the lower extremities. The average treatment protocol was 3 x per week for 30 minutes for a mean of 15-19 treatments and included physical therapy interventions such as therapeutic exercise, neuromuscular re-education and/or gait training.   After therapy was complete, 493 of 550 patients contacted agreed to provide answers to a health questionnaire.
Pain Endpoint:
Numeric Visual Analog scale from 0 - 10 (10 being the worst pain)
Results :

Mean pain reduction overall was 63.4%. 51.4% of patients who were on pain medications were able to reduce or eliminate their pain medications.

Pain response to MIRE is not based on the use of medication.

 

No Pain Meds During MIRE

DecreasedPain Meds

No Change in Pain Meds Changed Pain Meds
Group 1 Group 2 Group 3 Group 3
# of Patients
129 187 151 26
Male
66 72 63 13
Female
63 115 88 13
Age
(Range)

74
(53-94)

72

(44-90)
73

(46-93)
69

(54-94)
Duration of Pain (Months)a
41.5 ± 

31.4
49.9 ± 32.9 54.3 ± 35.3 54.7 ± 38.8
Number of Treatmentsa
15 ± 9.2 15 ± 8.2 16 ± 9.1 19 ± 8.9
Initial Paina
6.7 ± 2.4 7.2 ± 1.9 6.7 ± 2.3 7.3 ± 1.9
Post Paina
2.4 ± 2.2b 2.5 ± 2.2b 2.6 ± 2.0b 2.6 ± 1.9b
Mean Pain Decreasea
4.3 ± 2.5b 4.7 ± 2.1b 4.2 ± 2.3b 4.7 ± 2.4b
% Pain Reduction
64.2% 65.3% 62.3% 64.4%

a = mean ± SD.  b = P<0.0001 vs. initial pain. Meds = medications.
Changed Pain Meds indicates either a different dose or a different medication, or both.
Decreased Pain Meds indicates either a lowered dosage or a frequency or eliminated use of pain medications.

Conclusion:
MIRE, when administered as part of a physical therapy care plan prescribed by a physician, is associated with substantial lower extremity pain relief and the pain-relieving effects of Anodyne Therapy / MIRE appear to be independent of pain medication use.

To request more information about Anodyne Therapy Systems, please contact us.

  Quick Contact About Our Products SCI. LITERATURE Quick Info  
  About Anodyne Therapy INDIA
About Anodyne Therapy USA

Phone No : +91 80 6596 3132
Mobile: +91 87625 32901

Model MP480 - For professional use
Model MH120 - For Home use of the patient
Written Testimonials
Video Testimonials
Our Certifications
Overview
Clinical Research
Method of Action
Increases in Circulation
Study Summaries
Publications
Privacy policy
Refund and cancellation
Terms and condition
Delivery and shipping policy
 
  Copyright 2012 Anodyne Therapy  

 


Designed by
CKR INFOTECH